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Clinical trial results

βš–οΈ Legal
β—† Depends on context

A drug or therapy reports data from a clinical study, usually Phase 2 or Phase 3.

Typical size

30-150% for single-asset biotech

Timeframe

Instantaneous and permanent

Evidence

3 logged events

Why it moves the price

Trial data is the single input that decides whether an asset has any value. Success moves it toward approval and revenue; failure typically writes the programme to zero.

What separates a good call from a naive one

Even more binary than the approval that follows. Read the endpoint actually hit, not the press-release adjectives β€” statistically significant but clinically marginal results often sell off, and a safety signal can kill a drug that met its efficacy endpoint.

Measured impact

Measured: moves upLow confidence

Every logged event is measured against real closing prices: the move from the close before the event, compared with the S&P 500 over the same window.

Next day

+46.10%

Median
+9.58%
Moved up
100% of 3
vs S&P 500
+45.20%

After 1 week

+50.89%

Median
+9.20%
Moved up
100% of 3
vs S&P 500
+49.97%

After 1 month

+66.00%

Median
+64.69%
Moved up
100% of 3
vs S&P 500
+62.18%
Textbook view:β—† Depends on contexttypically 30-150% for single-asset biotech

The logged evidence is mixed, which is common for context-dependent factors. Based on 3 measured events.

The evidence (3)

Every row is a real event, measured against actual closing prices.

DateStockWhat happenedNext day1 week1 monthvs S&P
Feb 27, 2024VKTX

Phase 2 obesity data far exceeded expectations

Single-asset biotech: the whole company revalued on one readout.

+121.02%+137.37%+110.06%+120.84%
Nov 16, 2020MRNA

Covid vaccine interim efficacy reported at roughly 94%

+9.58%+9.20%+64.69%+8.33%
Nov 9, 2020PFE

Covid vaccine interim efficacy reported above 90%

Large-cap comparison: the same news moves a diversified pharma far less.

+7.69%+6.10%+23.24%+6.44%

Measured from historical closing prices. Past reactions do not guarantee future ones. Not financial advice.